The Deadly Foes of Spider-Man is a 4 part mini series featuring the Sinister Syndicate, which ran from May 1991 to August 1991.
The Sinister Syndicate is a group of supervillains in the Marvel Comics universe, who serve as a collection of lesser-known Spider-Man villains. The original incarnation of the Sinister Syndicate was organized by The Beetle and appeared in The Amazing Spider-Man #280 (September 1986) and was the focus of this mini-series.